Cargando…

Formulation and Evaluation of Pravastatin Sodium-Loaded PLGA Nanoparticles: In vitro–in vivo Studies Assessment

PURPOSE: Pravastatin sodium (PVS) is a hypolipidemic drug which suffers from extensive first-pass metabolism and short half-life. Poly(d,l-lactide-co-glycolide) (PLGA) is considered a promising carrier to improve its hypolipidemic and hepatoprotective activities. METHODS: PVS-loaded PLGA nanoparticl...

Descripción completa

Detalles Bibliográficos
Autores principales: Elsayed, Seham I, Girgis, Germeen N S, El-Dahan, Marwa S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936887/
https://www.ncbi.nlm.nih.gov/pubmed/36816332
http://dx.doi.org/10.2147/IJN.S394701