Cargando…

Formulation and Evaluation of Pravastatin Sodium-Loaded PLGA Nanoparticles: In vitro–in vivo Studies Assessment

PURPOSE: Pravastatin sodium (PVS) is a hypolipidemic drug which suffers from extensive first-pass metabolism and short half-life. Poly(d,l-lactide-co-glycolide) (PLGA) is considered a promising carrier to improve its hypolipidemic and hepatoprotective activities. METHODS: PVS-loaded PLGA nanoparticl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Elsayed, Seham I, Girgis, Germeen N S, El-Dahan, Marwa S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936887/ https://www.ncbi.nlm.nih.gov/pubmed/36816332 http://dx.doi.org/10.2147/IJN.S394701

Ejemplares similares

Chitosan-Coated PLGA Nanoparticles for Enhanced Ocular Anti-Inflammatory Efficacy of Atorvastatin Calcium
por: Arafa, Mona G, et al.
Publicado: (2020)

Formulation and Pathohistological Study of Mizolastine–Solid Lipid Nanoparticles–Loaded Ocular Hydrogels
por: El-Emam, Ghada Ahmed, et al.
Publicado: (2021)

Formulation Development and Evaluation of Pravastatin-Loaded Nanogel for Hyperlipidemia Management
por: Saraogi, Gaurav Kant, et al.
Publicado: (2022)

Formulation and In vitro Interaction of Rhodamine-B Loaded PLGA Nanoparticles with Cardiac Myocytes
por: Jonderian, Antranik, et al.
Publicado: (2016)

Endostar-loaded PEG-PLGA nanoparticles: in vitro and in vivo evaluation
por: Hu, Sanyuan, et al.
Publicado: (2010)

Formulation and Pharmacokinetic Evaluation of Microcapsules Containing Pravastatin Sodium Using Rats
por: Puttegowda, Venkatesh Dinnekere, et al.
Publicado: (2016)

5-Fluorouracil-Loaded PLGA Nanoparticles: Formulation, Physicochemical Characterisation, and In VitroAnti-Cancer Activity
por: Gahtani, Reem M., et al.
Publicado: (2023)

Memantine loaded PLGA PEGylated nanoparticles for Alzheimer’s disease: in vitro and in vivo characterization
por: Sánchez-López, Elena, et al.
Publicado: (2018)

The studies of PLGA nanoparticles loading atorvastatin calcium for oral administration in vitro and in vivo
por: Li, Zhenbao, et al.
Publicado: (2017)

Formulation of Antimicrobial Tobramycin Loaded PLGA Nanoparticles via Complexation with AOT
por: Hill, Marcus, et al.
Publicado: (2019)

Formulation and Optimization of Alogliptin-Loaded Polymeric Nanoparticles: In Vitro to In Vivo Assessment
por: Mohanty, Dibyalochan, et al.
Publicado: (2022)

Formulation, Colloidal Characterization, and In Vitro Biological Effect of BMP-2 Loaded PLGA Nanoparticles for Bone Regeneration
por: del Castillo-Santaella, Teresa, et al.
Publicado: (2019)

Ocular Inserts of Voriconazole-Loaded Proniosomal Gels: Formulation, Evaluation and Microbiological Studies
por: El-Emam, Ghada Ahmed, et al.
Publicado: (2020)

Docetaxel Loaded PEG-PLGA Nanoparticles: Optimized Drug Loading, In-vitro Cytotoxicity and In-vivo Antitumor Effect
por: Noori Koopaei, Mona, et al.
Publicado: (2014)

Development of Rifapentine-Loaded PLGA-Based Nanoparticles: In vitro Characterisation and in vivo Study in Mice
por: Liang, Qiuzhen, et al.
Publicado: (2020)

Formulation and Characterization of Antigen-loaded PLGA Nanoparticles for Efficient Cross-priming of the Antigen
por: Lee, Young-Ran, et al.
Publicado: (2011)

Phenytoin-loaded bioactive nanoparticles for the treatment of diabetic pressure ulcers: formulation and in vitro/in vivo evaluation
por: Sheir, Marwa M., et al.
Publicado: (2022)

Formulation, optimization and characterization of allantoin-loaded chitosan nanoparticles to alleviate ethanol-induced gastric ulcer: in-vitro and in-vivo studies
por: Aman, Reham Mokhtar, et al.
Publicado: (2021)

The targeting imaging and treatment capacity of gelsolin-targeted and paclitaxel-loaded PLGA nanoparticles in vitro and in vivo
por: Ji, Jiamei, et al.
Publicado: (2022)

Formulation and In Vitro Evaluation of Alendronate Sodium/PLGA Microspheres for Applications in Bone Related Disorders
por: DECA, A.G., et al.
Publicado: (2015)

Sustained in vitro interferon-beta release and in vivo toxicity of PLGA and PEG-PLGA nanoparticles
por: Fodor-Kardos, Andrea, et al.
Publicado: (2020)

Spanlastic-laden in situ gel as a promising approach for ocular delivery of Levofloxacin: In-vitro characterization, microbiological assessment, corneal permeability and in-vivo study
por: Agha, Omnia Ahmed, et al.
Publicado: (2023)

Formulation, Characterization And Evaluation Of Curcumin- Loaded PLGA- TPGS Nanoparticles For Liver Cancer Treatment
por: Chen, Xiao-ping, et al.
Publicado: (2019)

The Idiosyncratic Efficacy of Spironolactone-Loaded PLGA Nanoparticles Against Murine Intestinal Schistosomiasis
por: Abd El Hady, Walaa Ebrahim, et al.
Publicado: (2023)

Preparation of sustained release apremilast-loaded PLGA nanoparticles: in vitro characterization and in vivo pharmacokinetic study in rats
por: Anwer, Md Khalid, et al.
Publicado: (2019)

Applications of daunorubicin-loaded PLGA-PLL-PEG-Tf nanoparticles in hematologic malignancies: an in vitro and in vivo evaluation
por: Bao, Wen, et al.
Publicado: (2019)

Potential therapeutic effects of naringin loaded PLGA nanoparticles for the management of Alzheimer's disease: In vitro, ex vivo and in vivo investigation
por: Dashputre, Neelam L., et al.
Publicado: (2023)

Formulation, Cellular Uptake and Cytotoxicity of Thymoquinone-Loaded PLGA Nanoparticles in Malignant Melanoma Cancer Cells
por: Ibrahim, Wisam Nabeel, et al.
Publicado: (2020)

In vitro evaluation of 5-aminolevulinic acid (ALA) loaded PLGA nanoparticles
por: Shi, Lei, et al.
Publicado: (2013)

Förster Resonance Energy Transfer-Based Stability Assessment of PLGA Nanoparticles in Vitro and in Vivo
por: Swider, Edyta, et al.
Publicado: (2019)

Garcinol loaded vitamin E TPGS emulsified PLGA nanoparticles: preparation, physicochemical characterization, in vitro and in vivo studies
por: Gaonkar, Raghuvir H., et al.
Publicado: (2017)

Pravastatin Transdermal Patches: Effect of The Formulation and Two Different Lengths of Microneedles on In-vitro Percutaneous Absorption Studies
por: Castañeda, Pablo Serrano, et al.
Publicado: (2020)

Design, Formulation and in vivo Evaluation of Novel Honokiol-Loaded PEGylated PLGA Nanocapsules for Treatment of Breast Cancer
por: Haggag, Yusuf A, et al.
Publicado: (2020)

Formulation of PPAR-gamma agonist as surface modified PLGA nanoparticles for non-invasive treatment of diabetic retinopathy: in vitro and in vivo evidences
por: Laddha, Umesh D., et al.
Publicado: (2020)

Orally administered docetaxel-loaded chitosan-decorated cationic PLGA nanoparticles for intestinal tumors: formulation, comprehensive in vitro characterization, and release kinetics
por: Ünal, Sedat, et al.
Publicado: (2022)

Characterization of Human Erythrocytes as Potential Carrier for Pravastatin: An In Vitro Study
por: Harisa, Gamal El-din I., et al.
Publicado: (2011)

Formulation and Characterization of Ciprofloxacin loaded PLGA Microspheres for Applications in Orthopedic Infections
por: MOCANU, ANDREEA-GABRIELA, et al.
Publicado: (2017)

Eudragit(®)-S100 Coated PLGA Nanoparticles for Colon Targeting of Etoricoxib: Optimization and Pharmacokinetic Assessments in Healthy Human Volunteers
por: El-Maghawry, Enas, et al.
Publicado: (2020)

Pravastatin Provides Antioxidant Activity and Protection Of Erythrocytes Loaded Primaquine
por: Alanazi, Fars
Publicado: (2010)

Docetaxel-loaded PLGA and PLGA-PEG nanoparticles for intravenous application: pharmacokinetics and biodistribution profile
por: Rafiei, Pedram, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_44cofahr7mnjmf9trv72jpb0s8