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Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice

In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs). However, the pathogenic mechanisms that trigger HSC activation in leptin‐deficient obesity are still unknown. This study aimed to de...

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Detalles Bibliográficos
Autores principales: Kim, Kyung Eun, Lee, Jaewoong, Shin, Hyun Joo, Jeong, Eun Ae, Jang, Hye Min, Ahn, Yu Jeong, An, Hyeong Seok, Lee, Jong Youl, Shin, Meong Cheol, Kim, Soo Kyoung, Yoo, Won Gi, Kim, Won Ho, Roh, Gu Seob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936980/
https://www.ncbi.nlm.nih.gov/pubmed/35560370
http://dx.doi.org/10.1002/hep.32569