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Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice
In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs). However, the pathogenic mechanisms that trigger HSC activation in leptin‐deficient obesity are still unknown. This study aimed to de...
Autores principales: | Kim, Kyung Eun, Lee, Jaewoong, Shin, Hyun Joo, Jeong, Eun Ae, Jang, Hye Min, Ahn, Yu Jeong, An, Hyeong Seok, Lee, Jong Youl, Shin, Meong Cheol, Kim, Soo Kyoung, Yoo, Won Gi, Kim, Won Ho, Roh, Gu Seob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9936980/ https://www.ncbi.nlm.nih.gov/pubmed/35560370 http://dx.doi.org/10.1002/hep.32569 |
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