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Drosophila Ectoderm-expressed 4 modulates JAK/STAT pathway and protects flies against Drosophila C virus infection

Sterile alpha and HEAT/Armadillo motif-containing protein (SARM) is conserved in evolution and negatively regulates TRIF-dependent Toll signaling in mammals. The SARM protein from Litopenaeus vannamei and its Drosophila orthologue Ectoderm-expressed (Ect4) are also involved in immune defense against...

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Detalles Bibliográficos
Autores principales: Huang, Zongliang, Wang, Wei, Xu, Pengpeng, Gong, Shangyu, Hu, Yingshan, Liu, Yan, Su, Fang, Anjum, Khalid Mahmood, Deng, Wu-Min, Yang, Suping, Liu, Jiyong, Jiao, Renjie, Chen, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937023/
https://www.ncbi.nlm.nih.gov/pubmed/36817462
http://dx.doi.org/10.3389/fimmu.2023.1135625