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Inhibition of tiRNA-Gly-GCC ameliorates neointimal formation via CBX3-mediated VSMCs phenotypic switching

BACKGROUND AND AIM: tRNA-derived fragments (tRFs) are a new class of non-coding RNAs involved in a variety of pathological processes, but their biological functions and mechanisms in human aortic smooth muscle cells (HASMCs) phenotype transition and vascular intimal hyperplasia are unclear. METHODS/...

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Detalles Bibliográficos
Autores principales: Rong, Zhihua, Li, Fengshi, Zhang, Rui, Niu, Shuai, Di, Xiao, Ni, Leng, Liu, Changwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937027/
https://www.ncbi.nlm.nih.gov/pubmed/36818350
http://dx.doi.org/10.3389/fcvm.2023.1030635