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HIV-1 Tat induced microglial EVs leads to neuronal synaptodendritic injury: microglia-neuron cross-talk in NeuroHIV

AIM: Activation of microglial NLRP3 inflammasome is an essential contributor to neuroinflammation underlying HIV-associated neurological disorders (HAND). Under pathological conditions, microglia-derived-EVs (MDEVs) can affect neuronal functions by delivering neurotoxic mediators to recipient cells....

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Detalles Bibliográficos
Autores principales: Kannan, Muthukumar, Singh, Seema, Chemparathy, Divya T., Oladapo, Abiola A., Gawande, Dinesh Y., Dravid, Shashank M., Buch, Shilpa, Sil, Susmita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937449/
https://www.ncbi.nlm.nih.gov/pubmed/36812097
http://dx.doi.org/10.20517/evcna.2022.14