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HIV-1 Tat induced microglial EVs leads to neuronal synaptodendritic injury: microglia-neuron cross-talk in NeuroHIV
AIM: Activation of microglial NLRP3 inflammasome is an essential contributor to neuroinflammation underlying HIV-associated neurological disorders (HAND). Under pathological conditions, microglia-derived-EVs (MDEVs) can affect neuronal functions by delivering neurotoxic mediators to recipient cells....
Autores principales: | Kannan, Muthukumar, Singh, Seema, Chemparathy, Divya T., Oladapo, Abiola A., Gawande, Dinesh Y., Dravid, Shashank M., Buch, Shilpa, Sil, Susmita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937449/ https://www.ncbi.nlm.nih.gov/pubmed/36812097 http://dx.doi.org/10.20517/evcna.2022.14 |
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