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Mechanism of activation and biased signaling in complement receptor C5aR1

The complement system plays an important role in the innate immune response to invading pathogens. The complement fragment C5a is one of its important effector components and exerts diverse physiological functions through activation of the C5a receptor 1 (C5aR1) and associated downstream G protein a...

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Detalles Bibliográficos
Autores principales: Feng, Yuying, Zhao, Chang, Deng, Yue, Wang, Heli, Ma, Liang, Liu, Sicen, Tian, Xiaowen, Wang, Bo, Bin, Yan, Chen, Peipei, Yan, Wei, Fu, Ping, Shao, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937529/
https://www.ncbi.nlm.nih.gov/pubmed/36806352
http://dx.doi.org/10.1038/s41422-023-00779-2