Cargando…
Mechanism of activation and biased signaling in complement receptor C5aR1
The complement system plays an important role in the innate immune response to invading pathogens. The complement fragment C5a is one of its important effector components and exerts diverse physiological functions through activation of the C5a receptor 1 (C5aR1) and associated downstream G protein a...
Autores principales: | Feng, Yuying, Zhao, Chang, Deng, Yue, Wang, Heli, Ma, Liang, Liu, Sicen, Tian, Xiaowen, Wang, Bo, Bin, Yan, Chen, Peipei, Yan, Wei, Fu, Ping, Shao, Zhenhua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937529/ https://www.ncbi.nlm.nih.gov/pubmed/36806352 http://dx.doi.org/10.1038/s41422-023-00779-2 |
Ejemplares similares
-
The Complement Receptors C3aR and C5aR Are a New Class of Immune Checkpoint Receptor in Cancer Immunotherapy
por: Wang, Yu, et al.
Publicado: (2019) -
Orthosteric ligand selectivity and allosteric probe dependence at Hydroxycarboxylic acid receptor HCAR2
por: Cheng, Lin, et al.
Publicado: (2023) -
Complement Receptor C5aR1 Inhibition Reduces Pyroptosis in hDPP4-Transgenic Mice Infected with MERS-CoV
por: Jiang, Yuting, et al.
Publicado: (2019) -
Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1
por: Beach, Callum, et al.
Publicado: (2023) -
Osteoblast-specific overexpression of complement receptor C5aR1 impairs fracture healing
por: Bergdolt, Stephanie, et al.
Publicado: (2017)