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Discovery of Neuroprotective Agents Based on a 5-(4-Pyridinyl)-1,2,4-triazole Scaffold

[Image: see text] Parkinson’s disease (PD) is characterized by the death of dopaminergic neurons. The common histopathological hallmark in PD patients is the formation of intracellular proteinaceous accumulations. The main constituent of these inclusions is alpha-synuclein (α-syn), an intrinsically...

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Detalles Bibliográficos
Autores principales: Gitto, Rosaria, Vittorio, Serena, Bucolo, Federica, Peña-Díaz, Samuel, Siracusa, Rosalba, Cuzzocrea, Salvatore, Ventura, Salvador, Di Paola, Rosanna, De Luca, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937533/
https://www.ncbi.nlm.nih.gov/pubmed/35179861
http://dx.doi.org/10.1021/acschemneuro.1c00849