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Discovery of Neuroprotective Agents Based on a 5-(4-Pyridinyl)-1,2,4-triazole Scaffold
[Image: see text] Parkinson’s disease (PD) is characterized by the death of dopaminergic neurons. The common histopathological hallmark in PD patients is the formation of intracellular proteinaceous accumulations. The main constituent of these inclusions is alpha-synuclein (α-syn), an intrinsically...
Autores principales: | Gitto, Rosaria, Vittorio, Serena, Bucolo, Federica, Peña-Díaz, Samuel, Siracusa, Rosalba, Cuzzocrea, Salvatore, Ventura, Salvador, Di Paola, Rosanna, De Luca, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937533/ https://www.ncbi.nlm.nih.gov/pubmed/35179861 http://dx.doi.org/10.1021/acschemneuro.1c00849 |
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