Discovery of a Potent and Highly Selective Dipeptidyl Peptidase IV and Carbonic Anhydrase Inhibitor as “Antidiabesity” Agents Based on Repurposing and Morphing of WB-4101

[Image: see text] The management of patients with type 2 diabetes mellitus (T2DM) is shifting from cardio-centric to weight-centric or, even better, adipose-centric treatments. Considering the downsides of multidrug therapies and the relevance of dipeptidyl peptidase IV (DPP IV) and carbonic anhydra...

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Detalles Bibliográficos
Autores principales: Artasensi, Angelica, Angeli, Andrea, Lammi, Carmen, Bollati, Carlotta, Gervasoni, Silvia, Baron, Giovanna, Matucci, Rosanna, Supuran, Claudiu T., Vistoli, Giulio, Fumagalli, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937538/
https://www.ncbi.nlm.nih.gov/pubmed/36201615
http://dx.doi.org/10.1021/acs.jmedchem.2c01192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937538/
https://www.ncbi.nlm.nih.gov/pubmed/36201615
http://dx.doi.org/10.1021/acs.jmedchem.2c01192

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