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Increased chromatin accessibility promotes the evolution of a transcriptional silencer in Drosophila

The loss of discrete morphological traits, the most common evolutionary transition, is typically driven by changes in developmental gene expression. Mutations accumulating in regulatory elements of these genes can disrupt DNA binding sites for transcription factors patterning their spatial expressio...

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Detalles Bibliográficos
Autores principales: Ling, Liucong, Mühling, Bettina, Jaenichen, Rita, Gompel, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937571/
https://www.ncbi.nlm.nih.gov/pubmed/36800429
http://dx.doi.org/10.1126/sciadv.ade6529