Cargando…
Increased chromatin accessibility promotes the evolution of a transcriptional silencer in Drosophila
The loss of discrete morphological traits, the most common evolutionary transition, is typically driven by changes in developmental gene expression. Mutations accumulating in regulatory elements of these genes can disrupt DNA binding sites for transcription factors patterning their spatial expressio...
Autores principales: | Ling, Liucong, Mühling, Bettina, Jaenichen, Rita, Gompel, Nicolas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937571/ https://www.ncbi.nlm.nih.gov/pubmed/36800429 http://dx.doi.org/10.1126/sciadv.ade6529 |
Ejemplares similares
-
Ancestral and derived transcriptional enhancers share regulatory sequence and a pleiotropic site affecting chromatin accessibility
por: Xin, Yaqun, et al.
Publicado: (2020) -
ZBTB18 restricts chromatin accessibility and prevents transcriptional adaptations that drive metastasis
por: Wang, Ruishan, et al.
Publicado: (2023) -
XAF1 promotes anti-RNA virus immune responses by regulating chromatin accessibility
por: Kuang, Ming, et al.
Publicado: (2023) -
Dynamics and regulation of mitotic chromatin accessibility bookmarking at single-cell resolution
por: Yu, Qiaoni, et al.
Publicado: (2023) -
Regulatory encoding of quantitative variation in spatial activity of a Drosophila enhancer
por: Le Poul, Yann, et al.
Publicado: (2020)