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Genetic architecture of the white matter connectome of the human brain

White matter tracts form the structural basis of large-scale brain networks. We applied brain-wide tractography to diffusion images from 30,810 adults (U.K. Biobank) and found significant heritability for 90 node-level and 851 edge-level network connectivity measures. Multivariate genome-wide associ...

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Detalles Bibliográficos
Autores principales: Sha, Zhiqiang, Schijven, Dick, Fisher, Simon E., Francks, Clyde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937579/
https://www.ncbi.nlm.nih.gov/pubmed/36800424
http://dx.doi.org/10.1126/sciadv.add2870