Prelimbic Cortical Stimulation with L-methionine Enhances Cognition through Hippocampal DNA Methylation and Neuroplasticity Mechanisms

Declining global DNA methylation and cognitive impairment are reported to occur in the normal aging process. It is not known if DNA methylation plays a role in the efficacy of memory-enhancing therapies. In this study, aged animals were administered prelimbic cortical deep brain stimulation (PrL DBS...

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Detalles Bibliográficos
Autores principales: Poon, Chi Him, Liu, Yanzhi, Pak, Sojeong, Zhao, Robert Chunhua, Aquili, Luca, Tipoe, George Lim, Leung, Gilberto Ka-Kit, Chan, Ying-Shing, Yang, Sungchil, Fung, Man-Lung, Wu, Ed Xuekui, Lim, Lee Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937711/
https://www.ncbi.nlm.nih.gov/pubmed/36818556
http://dx.doi.org/10.14336/AD.2022.0706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937711/
https://www.ncbi.nlm.nih.gov/pubmed/36818556
http://dx.doi.org/10.14336/AD.2022.0706

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