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Prelimbic Cortical Stimulation with L-methionine Enhances Cognition through Hippocampal DNA Methylation and Neuroplasticity Mechanisms
Declining global DNA methylation and cognitive impairment are reported to occur in the normal aging process. It is not known if DNA methylation plays a role in the efficacy of memory-enhancing therapies. In this study, aged animals were administered prelimbic cortical deep brain stimulation (PrL DBS...
Autores principales: | Poon, Chi Him, Liu, Yanzhi, Pak, Sojeong, Zhao, Robert Chunhua, Aquili, Luca, Tipoe, George Lim, Leung, Gilberto Ka-Kit, Chan, Ying-Shing, Yang, Sungchil, Fung, Man-Lung, Wu, Ed Xuekui, Lim, Lee Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JKL International LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937711/ https://www.ncbi.nlm.nih.gov/pubmed/36818556 http://dx.doi.org/10.14336/AD.2022.0706 |
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