Sub-Retinal Injection of Human Lipofuscin in the Mouse - A Model of “Dry” Age-Related Macular Degeneration?

Lipofuscin (LF) accumulates during lifetime in the retinal pigment epithelium (RPE) and is thought to play a crucial role in intermediate and late age-related macular degeneration (AMD). In an attemt to simulate aged retina and to study response of retinal microglia and RPE cells to LF, we injected...

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Detalles Bibliográficos
Autores principales: Su, Nan, Hansen, Uwe, Plagemann, Tanja, Gäher, Karin, Leclaire, M. Dominik, König, Jeannette, Höhn, Annika, Grune, Tilman, Uhlig, Constantin E., Eter, Nicole, Heiduschka, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937713/
https://www.ncbi.nlm.nih.gov/pubmed/36818570
http://dx.doi.org/10.14336/AD.2022.0626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937713/
https://www.ncbi.nlm.nih.gov/pubmed/36818570
http://dx.doi.org/10.14336/AD.2022.0626

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