Traxoprodil Produces Antidepressant-Like Behaviors in Chronic Unpredictable Mild Stress Mice through BDNF/ERK/CREB and AKT/FOXO/Bim Signaling Pathway

Traxoprodil is a selective N-methyl-d-aspartate receptor subunit 2B (NR2B) receptor inhibitor with rapid and long-lasting antidepressant effects. However, the appropriate dosage, duration of administration, and underlying mechanism of traxoprodil's antidepressant effects remain unclear. The pur...

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Detalles Bibliográficos
Autores principales: Wang, Yahui, Liang, Zehuai, Song, Wenyue, Qin, Yu, Todd, Noah, Gao, Mingqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937761/
https://www.ncbi.nlm.nih.gov/pubmed/36819781
http://dx.doi.org/10.1155/2023/1131422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937761/
https://www.ncbi.nlm.nih.gov/pubmed/36819781
http://dx.doi.org/10.1155/2023/1131422

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