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Traxoprodil Produces Antidepressant-Like Behaviors in Chronic Unpredictable Mild Stress Mice through BDNF/ERK/CREB and AKT/FOXO/Bim Signaling Pathway
Traxoprodil is a selective N-methyl-d-aspartate receptor subunit 2B (NR2B) receptor inhibitor with rapid and long-lasting antidepressant effects. However, the appropriate dosage, duration of administration, and underlying mechanism of traxoprodil's antidepressant effects remain unclear. The pur...
Autores principales: | Wang, Yahui, Liang, Zehuai, Song, Wenyue, Qin, Yu, Todd, Noah, Gao, Mingqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937761/ https://www.ncbi.nlm.nih.gov/pubmed/36819781 http://dx.doi.org/10.1155/2023/1131422 |
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