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δ-Opioid Receptor Activation Inhibits Ferroptosis by Activating the Nrf2 Pathway in MPTP-Induced Parkinson Disease Models

INTRODUCTION: Recent studies suggest the involvement of ferroptosis in the pathogenesis of Parkinson disease (PD). δ-Opioid receptors (DORs) have neuroprotective effects in PD. It is not known whether the neuroprotective effects of DORs in PD are attributable to the inhibition of ferroptosis. Theref...

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Detalles Bibliográficos
Autores principales: Cai, Benchi, Zhong, Lifan, Liu, Yanhui, Xu, Qian, Chen, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937764/
https://www.ncbi.nlm.nih.gov/pubmed/36818224
http://dx.doi.org/10.1155/2023/4130937