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Neurotoxicity mechanism of aconitine in HT22 cells studied by microfluidic chip-mass spectrometry

Aconitine, a common and main toxic component of Aconitum, is toxic to the central nervous system. However, the mechanism of aconitine neurotoxicity is not yet clear. In this work, we had the hypothesis that excitatory amino acids can trigger excitotoxicity as a pointcut to explore the mechanism of n...

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Detalles Bibliográficos
Autores principales: Zhang, Yingrui, Chen, Shiyu, Fan, Fangfang, Xu, Ning, Meng, Xian-Li, Zhang, Yi, Lin, Jin-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937797/
https://www.ncbi.nlm.nih.gov/pubmed/36820076
http://dx.doi.org/10.1016/j.jpha.2022.11.007