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Integrated top-down and bottom-up proteomics mass spectrometry for the characterization of endogenous ribosomal protein heterogeneity

Ribosomes are abundant, large RNA-protein complexes that are the sites of all protein synthesis in cells. Defects in ribosomal proteins (RPs), including proteoforms arising from genetic variations, alternative splicing of RNA transcripts, post-translational modifications and alterations of protein e...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Cai, Qinghua, Luo, Yuxiang, Zhang, Yu, Li, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937802/
https://www.ncbi.nlm.nih.gov/pubmed/36820077
http://dx.doi.org/10.1016/j.jpha.2022.11.003