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EIF3D promotes resistance to 5‐fluorouracil in colorectal cancer through upregulating RUVBL1

BACKGROUND: As EIF3D is oncogenic in colorectal cancer (CRC) and is associated with multidrug resistance, this study aims to investigate whether and how EIF3D regulates resistance to 5‐fluorouracil (5‐Fu) in CRC. METHODS: EIF3D‐associated genes in CRC were predicted using bioinformatics tools. CRC c...

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Detalles Bibliográficos
Autores principales: Li, Chaobin, Lu, Kemei, Yang, Chenggang, Du, Wenfeng, Liang, Zhengkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9937894/
https://www.ncbi.nlm.nih.gov/pubmed/36592991
http://dx.doi.org/10.1002/jcla.24825