Intra‐ischemic hypothermia cardioprotection involves modulation of PTEN/Akt/ERK signaling and fatty acid oxidation

Therapeutic hypothermia (TH) provides cardioprotection from ischemia/reperfusion (I/R) injury. However, it remains unknown how TH regulates metabolic recovery. We tested the hypothesis that TH modulates PTEN, Akt, and ERK1/2, and improves metabolic recovery through mitigation of fatty acid oxidation...

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Detalles Bibliográficos
Autores principales: Justice, Cody N., Zhu, Xiangdong, Li, Jing, O'Donnell, J. Michael, Vanden Hoek, Terry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938006/
https://www.ncbi.nlm.nih.gov/pubmed/36807889
http://dx.doi.org/10.14814/phy2.15611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938006/
https://www.ncbi.nlm.nih.gov/pubmed/36807889
http://dx.doi.org/10.14814/phy2.15611

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