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PUM2 aggravates the neuroinflammation and brain damage induced by ischemia–reperfusion through the SLC7A11-dependent inhibition of ferroptosis via suppressing the SIRT1

Cerebral ischemia–reperfusion (I/R) injury occurs due to the restoration of blood perfusion after cerebral ischemia, which results in the damage of the brain structures and functions. Unfortunately, currently there are no effective methods for preventing and treating it. The pumilio 2 (PUM2) is a ty...

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Detalles Bibliográficos
Autores principales: Liu, Qingran, Liu, Yongchang, Li, Yan, Hong, Zhen, Li, Shaoquan, Liu, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938031/
https://www.ncbi.nlm.nih.gov/pubmed/35997855
http://dx.doi.org/10.1007/s11010-022-04534-w