A versatile, high-efficiency platform for CRISPR-based gene activation

CRISPR-mediated transcriptional activation (CRISPRa) is a powerful technology for inducing gene expression from endogenous loci with exciting applications in high throughput gain-of-function genomic screens and the engineering of cell-based models. However, current strategies for generating potent,...

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Detalles Bibliográficos
Autores principales: Heidersbach, Amy J., Dorighi, Kristel M., Gomez, Javier A., Jacobi, Ashley M., Haley, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938141/
https://www.ncbi.nlm.nih.gov/pubmed/36804928
http://dx.doi.org/10.1038/s41467-023-36452-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938141/
https://www.ncbi.nlm.nih.gov/pubmed/36804928
http://dx.doi.org/10.1038/s41467-023-36452-w

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