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A versatile, high-efficiency platform for CRISPR-based gene activation
CRISPR-mediated transcriptional activation (CRISPRa) is a powerful technology for inducing gene expression from endogenous loci with exciting applications in high throughput gain-of-function genomic screens and the engineering of cell-based models. However, current strategies for generating potent,...
Autores principales: | Heidersbach, Amy J., Dorighi, Kristel M., Gomez, Javier A., Jacobi, Ashley M., Haley, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938141/ https://www.ncbi.nlm.nih.gov/pubmed/36804928 http://dx.doi.org/10.1038/s41467-023-36452-w |
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