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How the histological structure of some lung cancers shaped almost 70 years of radiobiology

Pivotal research led by Louis Harold Gray in the 1950s suggested that oxygen plays a vital role during radiotherapy. By proving that tumours have large necrotic cores due to hypoxia and that hypoxic cells require significantly larger doses of ionising radiation to achieve the same cell kill, Thomlin...

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Detalles Bibliográficos
Autores principales: Worth, Katja R., Papandreou, Ioanna, Hammond, Ester M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938174/
https://www.ncbi.nlm.nih.gov/pubmed/36344595
http://dx.doi.org/10.1038/s41416-022-02041-9