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KIF15 is essential for USP10-mediated PGK1 deubiquitination during the glycolysis of pancreatic cancer

Glycolysis is the most predominant metabolic reprogramming of pancreatic cancer (PC), the underlying mechanism of which in PC cells remains unclear. In this study, we found for the first time that KIF15 promotes the glycolytic capacity of PC cells and PC tumor growth. Moreover, the expression of KIF...

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Detalles Bibliográficos
Autores principales: Quan, Gang, Xu, Jian, Wang, Jie, Liu, Xinyuan, Xu, Jichuan, Jiang, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938189/
https://www.ncbi.nlm.nih.gov/pubmed/36807568
http://dx.doi.org/10.1038/s41419-023-05679-2