Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Neuropsychiatric disorders (NPDs) are frequently co-morbid with epilepsy, but the biological basis of shared risk remains poorly understood. The 16p11.2 duplication is a copy number variant that confers risk for diverse NPDs including autism spectrum disorder, schizophrenia, intellectual disability...

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Detalles Bibliográficos
Autores principales: Forrest, Marc P., Dos Santos, Marc, Piguel, Nicolas H., Wang, Yi-Zhi, Hawkins, Nicole A., Bagchi, Vikram A., Dionisio, Leonardo E., Yoon, Sehyoun, Simkin, Dina, Martin-de-Saavedra, Maria Dolores, Gao, Ruoqi, Horan, Katherine E., George, Alfred L., LeDoux, Mark S., Kearney, Jennifer A., Savas, Jeffrey N., Penzes, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938216/
https://www.ncbi.nlm.nih.gov/pubmed/36808153
http://dx.doi.org/10.1038/s41467-023-36087-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938216/
https://www.ncbi.nlm.nih.gov/pubmed/36808153
http://dx.doi.org/10.1038/s41467-023-36087-x

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