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Impact of adjuvant chemotherapy and radiotherapy on tumour-infiltrating lymphocytes and PD-L1 expression in metastatic breast cancer

BACKGROUND: Chemotherapy and radiotherapy were postulated to induce an inflamed tumour microenvironment. We aimed to evaluate the effects of adjuvant chemotherapy/radiotherapy on tumour-infiltrating lymphocytes (TILs) and programmed death-ligand 1 (PD-L1) expression in metastatic breast cancer. METH...

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Detalles Bibliográficos
Autores principales: Yazaki, Shu, Salgado, Roberto, Shimoi, Tatsunori, Yoshida, Masayuki, Shiino, Sho, Kaneda, Tomoya, Kojima, Yuki, Sumiyoshi-Okuma, Hitomi, Nishikawa, Tadaaki, Sudo, Kazuki, Noguchi, Emi, Murata, Takeshi, Takayama, Shin, Suto, Akihiko, Ohe, Yuichiro, Yonemori, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938235/
https://www.ncbi.nlm.nih.gov/pubmed/36522476
http://dx.doi.org/10.1038/s41416-022-02072-2