Mismatch repair markers in preoperative and operative endometrial cancer samples; expression concordance and prognostic value

BACKGROUND: The endometrial cancer mismatch repair (MMR) deficient subgroup is defined by loss of MSH6, MSH2, PMS2 or MLH1. We compare MMR status in paired preoperative and operative samples and investigate the prognostic impact of differential MMR protein expression levels. METHODS: Tumour lesions...

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Detalles Bibliográficos
Autores principales: Berg, Hege F., Engerud, Hilde, Myrvold, Madeleine, Lien, Hilde E., Hjelmeland, Marta Espevold, Halle, Mari K., Woie, Kathrine, Hoivik, Erling A., Haldorsen, Ingfrid S., Vintermyr, Olav, Trovik, Jone, Krakstad, Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938259/
https://www.ncbi.nlm.nih.gov/pubmed/36482191
http://dx.doi.org/10.1038/s41416-022-02063-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938259/
https://www.ncbi.nlm.nih.gov/pubmed/36482191
http://dx.doi.org/10.1038/s41416-022-02063-3

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