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Mismatch repair markers in preoperative and operative endometrial cancer samples; expression concordance and prognostic value
BACKGROUND: The endometrial cancer mismatch repair (MMR) deficient subgroup is defined by loss of MSH6, MSH2, PMS2 or MLH1. We compare MMR status in paired preoperative and operative samples and investigate the prognostic impact of differential MMR protein expression levels. METHODS: Tumour lesions...
Autores principales: | Berg, Hege F., Engerud, Hilde, Myrvold, Madeleine, Lien, Hilde E., Hjelmeland, Marta Espevold, Halle, Mari K., Woie, Kathrine, Hoivik, Erling A., Haldorsen, Ingfrid S., Vintermyr, Olav, Trovik, Jone, Krakstad, Camilla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938259/ https://www.ncbi.nlm.nih.gov/pubmed/36482191 http://dx.doi.org/10.1038/s41416-022-02063-3 |
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