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Tracking the evolution of esophageal squamous cell carcinoma under dynamic immune selection by multi-omics sequencing

Intratumoral heterogeneity (ITH) has been linked to decreased efficacy of clinical treatments. However, although genomic ITH has been characterized in genetic, transcriptomic and epigenetic alterations are hallmarks of esophageal squamous cell carcinoma (ESCC), the extent to which these are heteroge...

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Detalles Bibliográficos
Autores principales: Cui, Sijia, McGranahan, Nicholas, Gao, Jing, Chen, Peng, Jiang, Wei, Yang, Lingrong, Ma, Li, Liao, Junfang, Xie, Tian, Xie, Congying, Enver, Tariq, Wu, Shixiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938262/
https://www.ncbi.nlm.nih.gov/pubmed/36807354
http://dx.doi.org/10.1038/s41467-023-36558-1