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Tracking the evolution of esophageal squamous cell carcinoma under dynamic immune selection by multi-omics sequencing
Intratumoral heterogeneity (ITH) has been linked to decreased efficacy of clinical treatments. However, although genomic ITH has been characterized in genetic, transcriptomic and epigenetic alterations are hallmarks of esophageal squamous cell carcinoma (ESCC), the extent to which these are heteroge...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938262/ https://www.ncbi.nlm.nih.gov/pubmed/36807354 http://dx.doi.org/10.1038/s41467-023-36558-1 |