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Prostate cancer cell-platelet bidirectional signaling promotes calcium mobilization, invasion and apoptotic resistance via distinct receptor-ligand pairs

Platelets play a crucial role in cancer and thrombosis. However, the receptor-ligand repertoire mediating prostate cancer (PCa) cell-platelet interactions and ensuing consequences have not been fully elucidated. Microvilli emanating from the plasma membrane of PCa cell lines (RC77 T/E, MDA PCa 2b) d...

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Detalles Bibliográficos
Autores principales: Garofano, Kaitlin, Rashid, Kameron, Smith, Michael, Brantner, Christine, Suwunnakorn, Sumanun, Diemert, David, Gordon, Olivia, Horvath, Anelia, Khan, Sikandar, Popratiloff, Anastas, Rhim, Johng, Sidahmed, Alfateh, Maggirwar, Sanjay B., O’Brien, Travis J., Perera, Minoli A., Lee, Norman H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938282/
https://www.ncbi.nlm.nih.gov/pubmed/36806315
http://dx.doi.org/10.1038/s41598-023-29450-x