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Phenotypic screening platform identifies statins as enhancers of immune cell-induced cancer cell death

BACKGROUND: High-throughput screening (HTS) of small molecule drug libraries has greatly facilitated the discovery of new cancer drugs. However, most phenotypic screening platforms used in the field of oncology are based solely on cancer cell populations and do not allow for the identification of im...

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Detalles Bibliográficos
Autores principales: Selvin, Tove, Berglund, Malin, Lenhammar, Lena, Jarvius, Malin, Nygren, Peter, Fryknäs, Mårten, Larsson, Rolf, Andersson, Claes R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938546/
https://www.ncbi.nlm.nih.gov/pubmed/36803614
http://dx.doi.org/10.1186/s12885-023-10645-4