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Proximity labeling reveals a new in vivo network of interactors for the histone demethylase KDM5

BACKGROUND: KDM5 family proteins are multi-domain regulators of transcription that when dysregulated contribute to cancer and intellectual disability. KDM5 proteins can regulate transcription through their histone demethylase activity in addition to demethylase-independent gene regulatory functions...

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Detalles Bibliográficos
Autores principales: Yheskel, Matanel, Sidoli, Simone, Secombe, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938590/
https://www.ncbi.nlm.nih.gov/pubmed/36803422
http://dx.doi.org/10.1186/s13072-023-00481-y