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Predicting gene knockout effects from expression data
BACKGROUND: The study of gene essentiality, which measures the importance of a gene for cell division and survival, is used for the identification of cancer drug targets and understanding of tissue-specific manifestation of genetic conditions. In this work, we analyze essentiality and gene expressio...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938619/ https://www.ncbi.nlm.nih.gov/pubmed/36803845 http://dx.doi.org/10.1186/s12920-023-01446-6 |