SIRT1/APE1 promotes the viability of gastric cancer cells by inhibiting p53 to suppress ferroptosis

Gastric cancer (GC) is a common cancer worldwide with high mortality. Sirtuin 1 (SIRT1) and apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) are abnormally expressed in GC cells and related to p53, which is involved in ferroptosis. Thus, we explore the mechanism via which SIRT1, APE1, and p53 im...

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Detalles Bibliográficos
Autores principales: Zhao, Huijin, Ding, Yuanyi, Zhang, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938643/
https://www.ncbi.nlm.nih.gov/pubmed/36820068
http://dx.doi.org/10.1515/med-2022-0620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938643/
https://www.ncbi.nlm.nih.gov/pubmed/36820068
http://dx.doi.org/10.1515/med-2022-0620

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