Deoxycholic acid exacerbates intestinal inflammation by modulating interleukin-1β expression and tuft cell proportion in dextran sulfate sodium-induced murine colitis

BACKGROUND: The etiology of inflammatory bowel disease (IBD) remains unclear. However, intestinal metabolism is known to be critical in the pathogenesis of IBD. Bile acid is one of the main intestinal metabolites, and its role in the pathogenesis of IBD is worthy of investigation. This study investi...

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Detalles Bibliográficos
Autores principales: Ju, Jingyi, Zhang, Cui, Yang, Jiaolan, Yang, Qinglu, Yin, Pengyun, Sun, Xiaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938654/
https://www.ncbi.nlm.nih.gov/pubmed/36819995
http://dx.doi.org/10.7717/peerj.14842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938654/
https://www.ncbi.nlm.nih.gov/pubmed/36819995
http://dx.doi.org/10.7717/peerj.14842

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