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Deoxycholic acid exacerbates intestinal inflammation by modulating interleukin-1β expression and tuft cell proportion in dextran sulfate sodium-induced murine colitis
BACKGROUND: The etiology of inflammatory bowel disease (IBD) remains unclear. However, intestinal metabolism is known to be critical in the pathogenesis of IBD. Bile acid is one of the main intestinal metabolites, and its role in the pathogenesis of IBD is worthy of investigation. This study investi...
Autores principales: | Ju, Jingyi, Zhang, Cui, Yang, Jiaolan, Yang, Qinglu, Yin, Pengyun, Sun, Xiaomin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938654/ https://www.ncbi.nlm.nih.gov/pubmed/36819995 http://dx.doi.org/10.7717/peerj.14842 |
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