ZLN005 improves the survival of polymicrobial sepsis by increasing the bacterial killing via inducing lysosomal acidification and biogenesis in phagocytes

Polymicrobial sepsis still has a high mortality rate despite the development of antimicrobial agents, elaborate strategies to protect major organs, and the investment of numerous medical resources. Mitochondrial dysfunction, which acts as the center of energy metabolism, is clearly the basis of path...

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Detalles Bibliográficos
Autores principales: Suzuki, Yosuke, Kami, Daisuke, Taya, Toshihiko, Sano, Arata, Ogata, Takehiro, Matoba, Satoaki, Gojo, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938763/
https://www.ncbi.nlm.nih.gov/pubmed/36820088
http://dx.doi.org/10.3389/fimmu.2023.1089905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938763/
https://www.ncbi.nlm.nih.gov/pubmed/36820088
http://dx.doi.org/10.3389/fimmu.2023.1089905

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