GSDME-mediated pyroptosis promotes the progression and associated inflammation of atherosclerosis

Pyroptosis, a type of Gasdermin-mediated cell death, contributes to an exacerbation of inflammation. To test the hypothesis that GSDME-mediated pyroptosis aggravates the progression of atherosclerosis, we generate ApoE and GSDME dual deficiency mice. As compared with the control mice, GSDME(−/−)/Apo...

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Detalles Bibliográficos
Autores principales: Wei, Yuanyuan, Lan, Beidi, Zheng, Tao, Yang, Lin, Zhang, Xiaoxia, Cheng, Lele, Tuerhongjiang, Gulinigaer, Yuan, Zuyi, Wu, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938904/
https://www.ncbi.nlm.nih.gov/pubmed/36807553
http://dx.doi.org/10.1038/s41467-023-36614-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938904/
https://www.ncbi.nlm.nih.gov/pubmed/36807553
http://dx.doi.org/10.1038/s41467-023-36614-w

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