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The PBX1/miR-141-miR-200a/EGR2/SOCS3 Axis; Integrative Analysis of Interaction Networks to Discover the Possible Mechanism of MiR-141 and MiR-200a-Mediated Th17 Cell Differentiation

BACKGROUND: Overexpression of miR-141 and miR-200a is known to be associated with the differentiation of T helper 17 (Th17) cells, which are key players in the pathophysiology of autoimmune disorders. However, the function and governing mechanism of these two microRNAs (miRNAs) in Th17 cell skewing...

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Detalles Bibliográficos
Autores principales: Bahmani, Leila, Baghi, Masoud, Peymani, Maryam, Javeri, Arash, Ghaedi, Kamran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Genetic Engineering and Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938929/
https://www.ncbi.nlm.nih.gov/pubmed/36811100
http://dx.doi.org/10.30498/ijb.2022.317078.3211