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TNF-α Regulates the Glucocorticoid Receptor Alpha Expression in Human Nasal Epithelial Cells Via p65-NF-κb and p38-MAPK Signaling Pathways
BACKGROUND: Tumor necrosis factor (TNF)-α induces changes in the glucocorticoid receptor (GR) isoforms’ expression in human nasal epithelial cells (HNECs) in chronic rhinosinusitis (CRS). OBJECTIVE: However, the underlying mechanism of TNF-α induced GR isoforms’ expression in HNECs remains unclear....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Institute of Genetic Engineering and Biotechnology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938934/ https://www.ncbi.nlm.nih.gov/pubmed/36811108 http://dx.doi.org/10.30498/ijb.2022.298590.3117 |