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Evaluation of Apoptosis, Cell Proliferation and Cell Cycle Progression by Inactivation of the NEAT1 Long Noncoding RNA in a Renal Carcinoma Cell Line Using CRISPR/Cas9

BACKGROUND: Long noncoding RNAs (lncRNAs) play an important role in cellular mechanisms including transcription, translation, and apoptosis. NEAT1 is one of the essential types of lncRNAs in humans that can bind to active genes and modify their transcription. NEAT1 upregulation in various forms of c...

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Detalles Bibliográficos
Autores principales: Haghighi, Nastaran, Doosti, Abbas, Kiani, Jafar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Genetic Engineering and Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938936/
https://www.ncbi.nlm.nih.gov/pubmed/36811109
http://dx.doi.org/10.30498/ijb.2022.310632.3180