The essential roles of FXR in diet and age influenced metabolic changes and liver disease development: a multi-omics study

BACKGROUND: Aging and diet are risks for metabolic diseases. Bile acid receptor farnesoid X receptor (FXR) knockout (KO) mice develop metabolic liver diseases that progress into cancer as they age, which is accelerated by Western diet (WD) intake. The current study uncovers the molecular signatures...

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Detalles Bibliográficos
Autores principales: Yang, Guiyan, Jena, Prasant K., Hu, Ying, Sheng, Lili, Chen, Shin-Yu, Slupsky, Carolyn M., Davis, Ryan, Tepper, Clifford G., Wan, Yu-Jui Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938992/
https://www.ncbi.nlm.nih.gov/pubmed/36803569
http://dx.doi.org/10.1186/s40364-023-00458-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938992/
https://www.ncbi.nlm.nih.gov/pubmed/36803569
http://dx.doi.org/10.1186/s40364-023-00458-9

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