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The essential roles of FXR in diet and age influenced metabolic changes and liver disease development: a multi-omics study
BACKGROUND: Aging and diet are risks for metabolic diseases. Bile acid receptor farnesoid X receptor (FXR) knockout (KO) mice develop metabolic liver diseases that progress into cancer as they age, which is accelerated by Western diet (WD) intake. The current study uncovers the molecular signatures...
Autores principales: | Yang, Guiyan, Jena, Prasant K., Hu, Ying, Sheng, Lili, Chen, Shin-Yu, Slupsky, Carolyn M., Davis, Ryan, Tepper, Clifford G., Wan, Yu-Jui Yvonne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938992/ https://www.ncbi.nlm.nih.gov/pubmed/36803569 http://dx.doi.org/10.1186/s40364-023-00458-9 |
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